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A nucleosome is a linear chromosome wound around the


A) nuclear membrane.
B) rRNA.
C) mRNA.
D) histone.
E) nucleolus.

F) C) and D)
G) B) and C)

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Helicase


A) unwinds DNA.
B) supercoils DNA.
C) unwinds RNA.
D) winds RNA.

E) A) and D)
F) C) and D)

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The enzyme that can proofread replicating DNA,detect incorrect bases,excise them,and correctly replace them is


A) DNA ligase.
B) DNA polymerase.
C) DNA helicase.
D) DNA gyrase.
E) primase.

F) None of the above
G) A) and C)

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The development of virulent,toxin-producing bacterial strains due to the presence of a temperate phage can occur through the process of:


A) bacterial conjugation.
B) transformation.
C) generalized transduction.
D) specialized transduction.

E) None of the above
F) B) and D)

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A bacteriophage transfers a random fragment of DNA of the previous host to the current host.This is an example of


A) conjugation.
B) generalized transduction.
C) specialized transduction.
D) creation of an Hfr cell.

E) B) and C)
F) C) and D)

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All of the following pertain to nitrogenous bases except


A) form pairs by hydrogen bonding.
B) guanine pairs with uracil.
C) adenine pairs with thymine.
D) cytosine and thymine are pyrimidines.
E) allows variation from one nucleotide to another which creates the encoded information.

F) A) and B)
G) B) and D)

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B

Full induction of the lactose operon requires


A) lactose present.
B) lactose and glucose present.
C) lactose present without glucose.
D) lactose and arabinose present.

E) None of the above
F) A) and C)

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DNA gyrase


A) unwinds DNA.
B) supercoils DNA.
C) cleaves DNA.
D) joins free DNA ends.

E) A) and C)
F) B) and C)

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This molecule is translated into an amino acid sequence:


A) ribosomal RNA
B) messenger RNA
C) transfer RNA
D) primer RNA
E) ribozymes

F) D) and E)
G) B) and D)

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The nontranscribed region of DNA to which RNA polymerase binds to initiate transcription is called the


A) promoter.
B) operator.
C) operon.
D) exon.
E) intron.

F) C) and D)
G) C) and E)

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DNA Polymerase III


A) synthesizes primer.
B) removes primer.
C) joins Okazaki fragments.
D) unzips the DNA helix.
E) proofreads new DNA.

F) B) and D)
G) None of the above

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Transcription occurs within the nucleus or at the nucleoid.

A) True
B) False

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True

A primer comprised of ____ is needed at the origin of nucleotide addition.


A) polymerase III
B) polymerase I
C) helicase
D) RNA
E) DNA

F) C) and E)
G) None of the above

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Looking at your results of the Ames test,using bacteriological agar medium plates lacking the amino acid histidine,you find that there are many colonies growing on the agar.Your interpretation of this result is:


A) the bacterium has turned its operon genes on,producing proteins necessary for growth.
B) the chemical being tested is mutagenic.
C) the bacterium does not have any plasmids,so it cannot grow on the medium.
D) the drug being tested has no inhibitory effect on the bacterium,therefore it is not a good antibiotic to give for treatment of disease.

E) A) and C)
F) A) and B)

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The duplication of a cell's DNA is called


A) mitosis.
B) replication.
C) transcription.
D) translation.
E) mutation.

F) C) and D)
G) A) and B)

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Synthesis of an inducible enzyme requires


A) repressor alone bound to operator.
B) substrate bound to repressor.
C) substrate bound to promoter.
D) corepressor and repressor binding to operator.

E) B) and D)
F) B) and C)

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A permanent,inheritable change in the genetic information is called a/n


A) translation.
B) transcription.
C) mutation.
D) alteration.
E) regeneration.

F) C) and E)
G) B) and C)

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Which of the following is not a type of microRNA?


A) tRNA
B) miRNA
C) antisense RNA
D) riboswitch
E) siRNA

F) A) and B)
G) A) and E)

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The enzyme that helps pack DNA into the cell by coiling the DNA into a tight bundle is


A) DNA ligase.
B) DNA polymerase.
C) DNA helicase.
D) DNA gyrase.
E) primase.

F) A) and C)
G) D) and E)

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D

Semiconservative replication refers to


A) each base bonding at the 1' position of the sugar.
B) a purine always bonding to a pyrimidine.
C) one helix strand that runs from the 5' to 3' direction and the other strand that runs from the 3' to 5' direction.
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule.

E) A) and D)
F) A) and C)

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