Question 1

A major source of naturally produced penicillin is the mold ______.

Accepted Answer

A)   Penicillium notatum
B)   Penicillium chrysogenum
C)   Penicillium familiaris
D)   Naturally produced penicillin is no longer used.E) B) and C)
F) C) and D)

Question 2

All _____ consist of a thiazolidine ring,a beta-lactam ring,and an R group.

Accepted Answer

A)   penicillins
B)   tetracyclines
C)   macrolides
D)   cephalosporins
E)   aminoglycosidesF) C) and D)
G) A) and E)

Question 3

Sulfonamides are analogs of PABA and,as a result,they inhibit _____ synthesis.

Accepted Answer

A)   protein
B)   DNA
C)   RNA
D)   folic acid
E)   phospholipidF) All of the above
G) B) and C)

Question 4

The antifungal drug that can be used to treat serious systemic fungal infections is ______.

Accepted Answer

A)   nystatin
B)   griseofulvin
C)   amphotericin B
D)   sulfa drugs
E)   metronidazoleF) B) and E)
G) B) and D)

Question 5

Which of the following is not a drug group used to treat fungal infections?

Accepted Answer

A)   Quinolones
B)   Macrolide polyene antibiotics
C)   Griseofulvin
D)   Synthetic azoles
E)   FlucytosineF) A) and E)
G) C) and E)

Question 6

The most selectively toxic drugs are those that

Accepted Answer

A)   cause damage to host tissues.
B)   target microbial sites that are not present in humans, e.g., the bacterial cell wall.
C)   target structures present in both microbes and humans, thus causing host tissue damage.
D)   cause allergic reactions in humans.E) B) and D)
F) A) and B)

Question 7

Which antimicrobial does not inhibit cell wall synthesis?

Accepted Answer

A)   Gentamicin
B)   Vancomycin
C)   Cephalosporins
D)   Penicillins
E)   CarbapenemsF) B) and C)
G) None of the above

Question 8

Which of the following is not used to treat malaria?

Accepted Answer

A)   Quinine
B)   Chloroquine
C)   Metronidazole
D)   Primaquine
E)   MeflaquineF) None of the above
G) A) and D)

Question 9

Indwelling catheter biofilm infections are more resistant to antibiotics than nonbiofilm infections.

Accepted Answer

A) True 
 B)False

Question 10

Selective toxicity should be avoided when developing a new antimicrobial drug.

Accepted Answer

A) True 
 B)False

Question 11

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superficial skin infections?

Accepted Answer

A)   Vancomycin
B)   Bacitracin
C)   Chloramphenicol
D)   Streptomycin
E)   ClindamycinF) B) and E)
G) C) and D)

Question 12

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Accepted Answer

A) True 
 B)False

Question 13

Ciprofloxacin is used to treat viral respiratory infections.

Accepted Answer

A) True 
 B)False

Question 14

What molecule will allow some bacteria to be resistant to many penicillins?

Accepted Answer

A)   Synercid
B)   Penicillinase
C)   Aztreonam
D)   Clavulanic acid
E)   ImipenemF) B) and C)
G) B) and E)

Question 15

Drugs that act by mimicking the normal substrate of an enzyme,thereby blocking its active site,are called ______.

Accepted Answer

A)   inhibitors
B)   blockers
C)   competitive inhibitors
D)   noncompetitive inhibitorsE) None of the above
F) A) and C)

Question 16

A chemical that inhibits beta-lactamase enzymes is ______.

Accepted Answer

A)   synercid
B)   penicillinase
C)   aztreonam
D)   clavulanic acid
E)   imipenemF) All of the above
G) A) and C)

Question 17

Important characteristics of antimicrobial drugs include

Accepted Answer

A)   low toxicity for human tissues.
B)   high toxicity against microbial cells.
C)   a lack of serious side effects in humans.
D)   stability and solubility in body tissues and fluids.
E)   All of the choices are correct.F) A) and D)
G) C) and D)

Question 18

Organisms have a tendency to develop resistance to beta-lactams,and humans can develop allergic reactions to them.A drug that also targets the cell wall and can be used as an alternative is ______.

Accepted Answer

A)   streptomycin
B)   vancomycin
C)   tetracycline
D)   chloramphenicol
E)   fluoroquinoloneF) B) and E)
G) A) and E)

Question 19

Sulfa drugs work on

Accepted Answer

A)   nucleic acid biosynthesis.
B)   ribosome biosynthesis.
C)   peptidoglycan biosynthesis.
D)   folic acid biosynthesis.E) A) and D)
F) A) and C)

Question 20

Which of the following phrases reflects an effective treatment of biofilms?

Accepted Answer

A)   Add DNase to the antibiotics to disrupt extracellular debris
B)   Interrupt quorum-sensing pathways, preventing signaling between cells
C)   Pre-treat with newly-discovered antimicrobials before exposure to established drugs
D)   All of the above have been shown to enhance biofilm elimination.E) B) and C)
F) A) and B)

Exam 12: Antimicrobial Treatment

Sulfa drugs work on

Correct AnswerverifiedShow Answer

Important characteristics of antimicrobial drugs include

Correct AnswerverifiedShow Answer

Organisms have a tendency to develop resistance to beta-lactams,and humans can develop allergic reactions to them.A drug that also targets the cell wall and can be used as an alternative is ______.

Correct AnswerverifiedShow Answer

What molecule will allow some bacteria to be resistant to many penicillins?

Correct AnswerverifiedShow Answer

The antifungal drug that can be used to treat serious systemic fungal infections is ______.

Correct AnswerverifiedShow Answer

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Correct AnswerverifiedShow Answer

A major source of naturally produced penicillin is the mold ______.

Correct AnswerverifiedShow Answer

Which antimicrobial does not inhibit cell wall synthesis?

Correct AnswerverifiedShow Answer

Ciprofloxacin is used to treat viral respiratory infections.

Correct AnswerverifiedShow Answer

Drugs that act by mimicking the normal substrate of an enzyme,thereby blocking its active site,are called ______.

Correct AnswerverifiedShow Answer

All _____ consist of a thiazolidine ring,a beta-lactam ring,and an R group.

Correct AnswerverifiedShow Answer

The most selectively toxic drugs are those that

Correct AnswerverifiedShow Answer

Which of the following phrases reflects an effective treatment of biofilms?

Correct AnswerverifiedShow Answer

Selective toxicity should be avoided when developing a new antimicrobial drug.

Correct AnswerverifiedShow Answer

A chemical that inhibits beta-lactamase enzymes is ______.

Correct AnswerverifiedShow Answer

Indwelling catheter biofilm infections are more resistant to antibiotics than nonbiofilm infections.

Correct AnswerverifiedShow Answer

Sulfonamides are analogs of PABA and,as a result,they inhibit _____ synthesis.

Correct AnswerverifiedShow Answer

What antibiotic is mixed with neomycin and polymyxin to make an antibiotic ointment (Neosporin) for superficial skin infections?

Correct AnswerverifiedShow Answer

Which of the following is not a drug group used to treat fungal infections?

Correct AnswerverifiedShow Answer

Which of the following is not used to treat malaria?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified