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Inflammatory responses are orchestrated by the immune system and are part of the body's third line of defense.

A) True
B) False

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Which of the following is not a mechanism employed by the human microbiota to contribute to the first line of defense?


A) It can phagocytose pathogens
B) It can lower the pH making the environment too acidic for pathogens to survive
C) It can out-compete pathogens for limited nutrients
D) It can train the immune cells to recognize antigenic markers
E) It can block potential binding sites on epithelial cells restricting adhesion,which is a necessary step for infection

F) A) and C)
G) B) and C)

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This body region is protected by fatty acids,acidic pH,lactic acid,and a tough cell barrier with its own normal biota.


A) Skin
B) Respiratory tract
C) Digestive tract
D) Urinary tract
E) Eyes

F) A) and B)
G) A) and C)

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The human microbiome is considered an important component of the first line of defense.  Which statement adequately reflects its role as a defensive barrier?


A) The human microbiota competes with pathogens for space and nutrients limiting their ability to cause infection,and trains the immune system to recognize antigens.
B) The organisms that comprise the microbiota are able to phagocytose potential pathogens,thereby eliminating them from the human host.
C) The human microbiome has evolved with the species so it is able to actively destroy pathogens by raising the body temperature when an infection by a pathogen occurs.
D) Cells in the human microbiome secrete cytokines that play a role in stimulating the immune response when a pathogen has entered the system.

E) A) and B)
F) C) and D)

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The ________ system of blood proteins acts to lyse foreign cells and viruses.


A) humoral immunity
B) cell-mediated
C) complement
D) lymphoid
E) None of the choices are correct.

F) A) and B)
G) D) and E)

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Diapedesis is the ________.


A) loss of blood due to hemorrhaging
B) production of only red blood cells
C) production of white blood cells,red blood cells,and platelets
D) plugging of broken vessels to stop bleeding
E) migration of white blood cells from the blood out to the tissues

F) B) and C)
G) A) and E)

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When monocytes migrate from the blood out to the tissues they are transformed by inflammatory mediators to develop into ________.


A) primary phagocytes
B) neutrophils
C) killer T cells
D) cytotoxic T cells
E) macrophages

F) A) and E)
G) None of the above

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The mother of a 6-year-old child brings her daughter to the pediatrician's office because she has had a sore throat, cough, and fever for several days. She reports a fever up to 104°F that worsens at night, but seems to respond to treatment with acetaminophen. The child has not been eating or drinking well because she says, "it hurts to swallow." She is ill appearing, and does not seem interested in playing with the toys that are in the examination room. The physician notes a thick, white exudate on both of the patient's tonsils, which also seem enlarged. A throat culture and complete blood count with differential is ordered. -The nurse examines the child's tonsils while preparing to swab them with the culture swab.A white pustule coating is noted to be covering the tonsils.What is this pus composed of? 


A) Waste from red blood cells
B) Live bacteria
C) Fibrin threads
D) White blood cells and debris from phagocytosis

E) A) and D)
F) All of the above

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Immune system cells differentiate between self and foreign cells by their ________.


A) cell walls
B) biota
C) markers
D) skin
E) cell processes

F) B) and D)
G) A) and D)

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During what process are hypochlorite and hydrogen peroxide produced to destroy bacteria and inhibit viral replication?


A) Inflammation
B) Phagocytosis
C) Interferon production
D) Complement production
E) Bradykinin

F) A) and C)
G) B) and E)

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The blood cells that function in allergic reactions and inflammation,contain peroxidase and lysozyme,and particularly target parasitic worms and fungi are ________.


A) basophils
B) eosinophils
C) neutrophils
D) monocytes
E) lymphocytes

F) A) and B)
G) A) and D)

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Which of the following is incorrect about complement?


A) Is composed of at least 20 blood proteins
B) Only appears in the blood during a response to a pathogen
C) Acts in a cascade reaction
D) Involves a classical pathway
E) Involves an alternate pathway

F) A) and B)
G) C) and D)

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The production of interferon will protect the host cell from a viral infection.

A) True
B) False

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