Question 1

The primary purpose of viral cultivation is ________.

Accepted Answer

A)  to isolate and identify viruses in clinical specimens
B)  to prepare viruses for vaccines
C)  to do detailed research on viral structure,lifestyle,genetics,and effects on host cells
D)  All of the choices are correctE) B) and C)
F) All of the above D

Question 2

You are running an experiment in calf serum,which cannot be autoclaved because proteins essential to your protocol will be denatured.  You decide to filter sterilize the serum since the 0.22μm filter is small enough to block any bacteria that may contaminate your tissue culture.  The success of this procedure hinges on the fact that ________.

Accepted Answer

A)  the presence of viruses in your serum is inconsequential to your experiment
B)  some of the bacteria will still be allowed to filter through
C)  viruses,as well as bacteria,will also be blocked by the 0.22μm pore size
D)  the proteins in the serum are also blocked by the pore sizeE) A) and D)
F) A) and C)

Question 3

Viruses are unable to multiply outside of a host cell.

Accepted Answer

A) True 
 B)False

Question 4

An RN in a pediatric emergency department performs a triage patient on a 13-month-old male. The patient's father states he had difficulty waking his son from a nap that afternoon. Additionally, the infant had difficulty crawling and had difficulty with feeding the following morning. The RN observes that the patient has a weak cry. Upon further assessment, the patient's father noted that the infant had ingested fresh honey on his toast at breakfast yesterday. The medical team suspects Clostridium botulinum infection due to the ingestion of bacterial endospores.
-Even though it is a bacterium,Clostridium botulinum can be made more pathogenic once infected with a(n) ________.

Accepted Answer

A)  bacteriophage
B)  oncogene
C)  plaque
D)  retrovirusE) B) and C)
F) A) and C)

Question 5

Which of the following will not support viral cultivation?

Accepted Answer

A)  Live lab animals
B)  Embryonated bird eggs
C)  Primary cell cultures
D)  Continuous cell cultures
E)  All of the choices will support viral cultivation.F) B) and E)
G) B) and D)

Question 6

T-even phages ________.

Accepted Answer

A)  include the poxviruses
B)  infect Escherichia coli cells
C)  enter host cells by engulfment
D)  have helical capsids
E)  All of the choices are correctF) A) and E)
G) D) and E)

Question 7

When a bacterium acquires a trait from its temperate phage,it is called ________.

Accepted Answer

A)  transformation
B)  lysogenic conversion
C)  viral persistence
D)  transcription
E)  translationF) A) and E)
G) B) and D)

Question 8

Which of the following is not a characteristic of a transformed cell?

Accepted Answer

A)  Viral nucleic acid integrated into host DNA
B)  Decreased growth rate
C)  Alterations in chromosomes
D)  Changes in cell surface molecules
E)  Capacity to divide indefinitelyF) A) and B)
G) All of the above

Question 9

One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) ________ capsid.

Accepted Answer

A)  spiked
B)  complex
C)  icosahedral
D)  helical
E)  buckeyballF) A) and D)
G) A) and C)

Question 10

Viral nucleic acids include which of the following?

Accepted Answer

A)  Double-stranded DNA
B)  Single-stranded DNA
C)  Double-stranded RNA
D)  Single-stranded RNA
E)  All of the choices are correctF) A) and E)
G) A) and D) E

Question 11

An ideal antiviral drug would be one that killed the host cell,effectively preventing the virus from replicating.

Accepted Answer

A) True 
 B)False  False

Question 12

Oncoviruses include all the following except ________.

Accepted Answer

A)  hepatitis B virus
B)  measles virus
C)  papillomavirus
D)  HTLV I
E)  Epstein-Barr virusF) A) and B)
G) All of the above

Question 13

A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.

Accepted Answer

A)  embryo
B)  cell
C)  plaque
D)  bacteriophage
E)  eggF) B) and D)
G) B) and C)

Question 14

Uncoating of viral nucleic acid ________.

Accepted Answer

A)  does not occur in bacteriophage multiplication
B)  involves enzymatic destruction of the capsid
C)  releases viral nucleic acid into the cell
D)  occurs before replication
E)  All of the choices are correctF) A) and B)
G) A) and C)

Question 15

Viruses attach to their hosts via ________.

Accepted Answer

A)  host glycoproteins
B)  host phospholipids
C)  viral phospholipids
D)  viral flagella
E)  All of the choices are correctF) A) and B)
G) A) and E)

Question 16

When a virus enters a host cell,the viral genes redirect the genetic and metabolic activities of the host cell.

Accepted Answer

A) True 
 B)False

Question 17

Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild cold-like symptoms in most individuals,but can be more serious in infants and the elderly.RSV is so-named because ________.

Accepted Answer

A)  it causes the fusion of damaged host cells,forming a large,multinucleated cell
B)  it causes the proliferation of inclusion bodies within the host cell
C)  it causes a persistent infection in the host
D)  it transforms the host cell,causing cancerE) B) and C)
F) B) and D)

Question 18

The development of antiviral drug therapy is difficult because ________.

Accepted Answer

A)  viruses are obligate intracellular parasites so the host cell can be harmed by the drug
B)  viruses do not have specific replication cycles that can be targeted
C)  viruses do not contain genetic material
D)  their life cycles do not have distinctive stagesE) None of the above
F) C) and D)

Question 19

Viruses are ultramicroscopic because they range in size from 2 mm to 450 mm.

Accepted Answer

A) True 
 B)False

Question 20

What structures are used by bacteriophages to attach to host cell receptors?

Accepted Answer

A)  Sheath
B)  Tail fibers
C)  Nucleic acid
D)  Capsid head
E)  None of the choices are correctF) C) and D)
G) None of the above

Exam 5: Viral Structure and Multiplication

The primary purpose of viral cultivation is ________.

Correct Answer
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D

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Viruses are unable to multiply outside of a host cell.

Correct Answer
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Correct Answer
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Which of the following will not support viral cultivation?

Correct Answer
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T-even phages ________.

Correct Answer
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When a bacterium acquires a trait from its temperate phage,it is called ________.

Correct Answer
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Which of the following is not a characteristic of a transformed cell?

Correct Answer
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One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) ________ capsid.

Correct Answer
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Viral nucleic acids include which of the following?

Correct Answer
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E

An ideal antiviral drug would be one that killed the host cell,effectively preventing the virus from replicating.

Correct Answer
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False

Oncoviruses include all the following except ________.

Correct Answer
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A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.

Correct Answer
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Uncoating of viral nucleic acid ________.

Correct Answer
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Viruses attach to their hosts via ________.

Correct Answer
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When a virus enters a host cell,the viral genes redirect the genetic and metabolic activities of the host cell.

Correct Answer
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Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild cold-like symptoms in most individuals,but can be more serious in infants and the elderly.RSV is so-named because ________.

Correct Answer
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The development of antiviral drug therapy is difficult because ________.

Correct Answer
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Viruses are ultramicroscopic because they range in size from 2 mm to 450 mm.

Correct Answer
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What structures are used by bacteriophages to attach to host cell receptors?

Correct Answer
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Exam 5: Viral Structure and Multiplication

The primary purpose of viral cultivation is ________.

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Viruses are unable to multiply outside of a host cell.

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Which of the following will not support viral cultivation?

Correct AnswerverifiedShow Answer

T-even phages ________.

Correct AnswerverifiedShow Answer

When a bacterium acquires a trait from its temperate phage,it is called ________.

Correct AnswerverifiedShow Answer

Which of the following is not a characteristic of a transformed cell?

Correct AnswerverifiedShow Answer

One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) ________ capsid.

Correct AnswerverifiedShow Answer

Viral nucleic acids include which of the following?

Correct AnswerverifiedE

An ideal antiviral drug would be one that killed the host cell,effectively preventing the virus from replicating.

Correct AnswerverifiedFalse

Oncoviruses include all the following except ________.

Correct AnswerverifiedShow Answer

A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.

Correct AnswerverifiedShow Answer

Uncoating of viral nucleic acid ________.

Correct AnswerverifiedShow Answer

Viruses attach to their hosts via ________.

Correct AnswerverifiedShow Answer

When a virus enters a host cell,the viral genes redirect the genetic and metabolic activities of the host cell.

Correct AnswerverifiedShow Answer

Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild cold-like symptoms in most individuals,but can be more serious in infants and the elderly.RSV is so-named because ________.

Correct AnswerverifiedShow Answer

The development of antiviral drug therapy is difficult because ________.

Correct AnswerverifiedShow Answer

Viruses are ultramicroscopic because they range in size from 2 mm to 450 mm.

Correct AnswerverifiedShow Answer

What structures are used by bacteriophages to attach to host cell receptors?

Correct AnswerverifiedShow Answer

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E

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False

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