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Vaccines to prevent fungal infection are widely available because attenuated strains are safe.

A) True
B) False

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Aspergillus causes both mycoses and mycotoxicosis.

A) True
B) False

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Systemic infections with fungus are difficult to treat because fungi are metabolically similar to humans,so antifungal therapies are sometimes complicated by side effects.

A) True
B) False

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Which of the following is NOT a major contributor to opportunistic mycoses?


A) an invasive medical procedure
B) growth of fungus in food
C) immunosuppressive therapy
D) severe malnutrition
E) chronic diseases like diabetes

F) B) and D)
G) A) and B)

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Which of the following techniques reveal(s) the presence of fungal cells in tissues?


A) Gram staining
B) KOH treatment
C) Gomori methenamine silver (GMS) staining
D) Gram staining combined with KOH treatment
E) both KOH treatment and Gomori methenamine silver (GMS) staining

F) A) and E)
G) B) and D)

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Clusters of budding yeast and branching pseudohyphae are consistent with (candidiasis/dermatophytosis/histoplasmosis).

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Which of the following contributes to the pathogenesis of Cryptococcus neoformans?


A) the ability to produce hyphae which penetrate tissues
B) the production of leukocidins
C) the production of mucinase
D) the ability to resist killing after phagocytosis
E) the production of melanin and the presence of a phagocyte-resistant capsule

F) B) and E)
G) A) and C)

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The opportunistic pathogen ________ is metabolically and morphologically distinctive from other fungi and is not effectively treated with antifungal medications.


A) Candida albicans
B) Blastomyces dermatitidis
C) Aspergillus
D) Microsporum
E) Pneumocystis jirovecii

F) C) and E)
G) D) and E)

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Histoplasma and Coccidioides produce tuberculosis-like damage to the lungs that can be seen on X-ray images.

A) True
B) False

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Which of the following dermatophytes infects hair as well as skin?


A) Microsporum canis
B) Malassezia furfur
C) Fonsecaea pedrosoi
D) Epidermophyton floccosum
E) Trichophyton rubrum

F) A) and E)
G) C) and D)

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The monomorphic fungus Rhizopus is a(n)


A) common bread mold.
B) toxic mushroom.
C) opportunistic pathogen.
D) true pathogen.
E) common bread mold and an opportunistic pathogen.

F) C) and D)
G) B) and E)

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Fungi that cause systemic mycoses are uniformly acquired by ingesting contaminated food.

A) True
B) False

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Compare and contrast dermatophytosis and pityriasis.

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Both are noninvasive fungal infections o...

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Pityriasis,characterized by patches of hyperpigmented and depigmented skin on the trunk and arms,is due to cutaneous infection with


A) Epidermophyton floccosum.
B) Cryptococcus neoformans.
C) Malassezia furfur.
D) Microsporum canis.
E) Trichophyton rubrum.

F) A) and C)
G) C) and E)

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Chronic low-level ingestion of ________ may cause liver cancer.


A) aflatoxin
B) aspergillin
C) ergotamine
D) phalloidin
E) psilocybin

F) A) and B)
G) A) and C)

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Ringworm is caused by


A) worms infected with fungi invading the skin.
B) dermatophytes that have invaded deep into the living tissue.
C) dermatophytes growing in the outer dead tissue layers of the skin (epidermis) .
D) a hypersensitivity caused by superficial contact with dermatophytes.
E) toxins produced by dermatophytes.

F) B) and D)
G) C) and D)

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The production of distinctively (smooth/bumpy/spiny)spores is diagnostic for Histoplasma capsulatum.

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Blastomyces dermatitidis occurs in the (eastern/central/southwestern/western)part of North America.

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Which of the following statements about Malassezia is FALSE?


A) It is part of the microbiota of the skin.
B) It causes phaeohyphomycosis.
C) It is a basidomycete.
D) It causes pityriasis.
E) It tends to develop into a chronic infection.

F) A) and E)
G) A) and C)

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The opportunistic infection known as (aspergillosis/cryptococcosis/sporotrichosis)may develop into a series of nodular,pus-filled lesions on a limb.

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