Question 1

The monomer subunit of immunoglobulin molecules has all the following except ________.

Accepted Answer

A)   two identical heavy polypeptide chains
B)   two identical light polypeptide chains
C)   disulfide bonds between polypeptide chains
D)   four antigen binding sites
E)   a variable and constant region on each polypeptide chainF) All of the above
G) None of the above

Question 2

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is ________.

Accepted Answer

A)   IgA
B)   IgD
C)   IgE
D)   IgG
E)   IgMF) C) and D)
G) A) and D)

Question 3

The most significant cells in graft rejection are ________.

Accepted Answer

A)   helper T cells
B)   suppressor T cells
C)   cytotoxic T cells
D)   delayed hypersensitivity T cells
E)   natural killer (NK)  cellsF) A) and E)
G) C) and E)

Question 4

Which of the following explanations correctly represents how this patient could have been protected from chickenpox infection?

Accepted Answer

A)   He would not have been infected if he were breastfed as a baby because he would have passive natural immunity.
B)   He would not have been infected if his mother had gamma globulin administered during pregnancy because he would have passive artificial immunity.
C)   He could have been protected from infection if he received active artificial immunity through the form of a vaccine.
D)   He may have a primary immunodeficiency disease because healthy humans are not typically infected with chickenpox.E) A) and D)
F) All of the above

Question 5

An example of natural active immunity would be ________.

Accepted Answer

A)   chickenpox infection followed by lifelong immunity
B)   chickenpox vaccine, which triggers extended immunity to chickenpox
C)   giving a person immune serum globulins to chickenpox virus after exposure to the disease
D)   a fetus acquiring maternal IgG to the chickenpox virus across the placenta
E)   None of the choices are correct.F) C) and E)
G) C) and D)

Question 6

The immunoglobulin class that has a dimer form found in mucus, saliva, colostrum, and other body secretions is ________.

Accepted Answer

A)   IgA
B)   IgD
C)   IgE
D)   IgG
E)   IgMF) B) and D)
G) All of the above

Question 7

Lymphocyte maturation involves ________.

Accepted Answer

A)   hormonal signals that initiate development
B)   B cells maturing in bone marrow sites
C)   T cells maturing in the thymus
D)   release of mature lymphocytes to begin migration to various lymphoid organs
E)   All of the choices are correct.F) B) and D)
G) A) and B)

Question 8

Which statement is true regarding lymphocyte specificity?

Accepted Answer

A)   Genetic rearrangement in the DNA that codes for antigen receptors results in up to 10 trillion permutations in the variable regions of B- and T lymphocyte-receptors.
B)   There is a different gene for every possible antigen that a lymphocyte may encounter.
C)   B lymphocytes have specificity for a large number of different antigens, however T lymphocytes can recognize only 500 antigens corresponding to the number of gene segments that code for the antigen receptors.
D)   B- and T cell-receptors are identical and both recognize up to 500 antigens corresponding to the gene segments that code for the antigen receptor variable regions.E) B) and C)
F) A) and B)

Question 9

An example of artificial active immunity would be ________.

Accepted Answer

A)   chickenpox infection followed by lifelong immunity
B)   chickenpox vaccine which triggers extended immunity to chickenpox
C)   giving a person immune serum globulins to chickenpox virus after exposure to the disease
D)   a fetus acquiring maternal IgG to the chickenpox virus across the placenta
E)   None of the choices are correct.F) C) and D)
G) B) and E)

Question 10

Which form of acquired immunity is the patient developing by having this infection?

Accepted Answer

A)   Active natural immunity
B)   Passive natural immunity
C)   Active artificial immunity
D)   Passive artificial immunityE) A) and B)
F) None of the above

Question 11

During which response to the antigen do we display a latent period of no secretory antibody synthesis?

Accepted Answer

A)   Primary
B)   Secondary
C)   Tertiary
D)   Quaternary
E)   Memory responseF) A) and E)
G) None of the above

Question 12

MHC molecules are found on each of the following cells except ________.

Accepted Answer

A)   leukocytes
B)   eosinophils
C)   epithelial cells
D)   red blood cells
E)   islet of Langerhans cellsF) C) and D)
G) A) and D)

Question 13

After secreting antibodies during an immune response, plasma cells then differentiate into memory cells.

Accepted Answer

A) True 
 B)False

Question 14

The importance of clonal deletion is that ________.

Accepted Answer

A)   lymphocytes with receptors that recognize self markers are eliminated to preserve immune tolerance
B)   worn-out lymphocytes are destroyed to make way for new cells
C)   lymphocytes that have been activated during antigen exposure are then removed when the individual recovers
D)   clones of cells that have the same receptor are deleted to avoid redundancyE) None of the above
F) A) and B)

Question 15

The immunoglobulins found on the surface of B cells are ________.

Accepted Answer

A)   IgM only
B)   IgG only
C)   IgD only
D)   IgM and IgD
E)   IgD and IgEF) B) and D)
G) C) and E)

Question 16

Antibodies directed to alloantigen from one organism often cross-react with an alloantigen from another organism.

Accepted Answer

A) True 
 B)False

Question 17

A naive B lymphocyte has receptors bound to its surface that ________.

Accepted Answer

A)   are all specific for the same antigen
B)   have a variable region that is different to the variable regions of B cell-receptors embedded in other naive B lymphocytes
C)   is one of up to 10 trillion possible protein configurations due to genetic rearrangement
D)   will have the same variable region as the antibodies that will be secreted following a challenge by the corresponding antigen
E)   All of the choices are true statements concerning B lymphocyte-receptors.F) D) and E)
G) B) and C)

Question 18

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 19

The secondary response to an antigen is faster and bigger than the primary response.

Accepted Answer

A) True 
 B)False

Question 20

When the patient's mother expresses concern about his sister being reinfected with chickenpox, what is the most appropriate response?

Accepted Answer

A)   Your concerns are valid, but his sister developed an active natural immunity to chickenpox because she has already been infected.
B)   Your concerns are valid and there is a high likelihood that his sister will become infected again. We should probably administer the vaccine.
C)   Your concerns are valid and there is no way to protect his sister from becoming reinfected except to keep her at least 15 feet from your son at all times.
D)   Your concerns are valid and if his sister is reinfected, her symptoms will be less severe than her initial chickenpox infection.E) A) and B)
F) A) and C)

Exam 13: Host Defenses Ii: Specific Immunity and Immunization

Which form of acquired immunity is the patient developing by having this infection?

Correct AnswerverifiedShow Answer

During which response to the antigen do we display a latent period of no secretory antibody synthesis?

Correct AnswerverifiedShow Answer

After secreting antibodies during an immune response, plasma cells then differentiate into memory cells.

Correct AnswerverifiedShow Answer

The immunoglobulins found on the surface of B cells are ________.

Correct AnswerverifiedShow Answer

When the patient's mother expresses concern about his sister being reinfected with chickenpox, what is the most appropriate response?

Correct AnswerverifiedShow Answer

An example of natural active immunity would be ________.

Correct AnswerverifiedShow Answer

Which of the following explanations correctly represents how this patient could have been protected from chickenpox infection?

Correct AnswerverifiedShow Answer

Which statement is true regarding lymphocyte specificity?

Correct AnswerverifiedShow Answer

Lymphocyte maturation involves ________.

Correct AnswerverifiedShow Answer

The most significant cells in graft rejection are ________.

Correct AnswerverifiedShow Answer

MHC molecules are found on each of the following cells except ________.

Correct AnswerverifiedShow Answer

The immunoglobulin class that has a dimer form found in mucus, saliva, colostrum, and other body secretions is ________.

Correct AnswerverifiedShow Answer

A naive B lymphocyte has receptors bound to its surface that ________.

Correct AnswerverifiedShow Answer

The importance of clonal deletion is that ________.

Correct AnswerverifiedShow Answer

The secondary response to an antigen is faster and bigger than the primary response.

Correct AnswerverifiedShow Answer

Antibodies directed to alloantigen from one organism often cross-react with an alloantigen from another organism.

Correct AnswerverifiedShow Answer

Antibody molecules circulate in lymph, blood, and tissue fluids.

Correct AnswerverifiedShow Answer

An example of artificial active immunity would be ________.

Correct AnswerverifiedShow Answer

The monomer subunit of immunoglobulin molecules has all the following except ________.

Correct AnswerverifiedShow Answer

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is ________.

Correct AnswerverifiedShow Answer

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